I Tested the Best Probiotic Drops for Newborns: My Honest Review and Top Picks

As a new parent, I quickly realized how important it is to support my baby’s delicate digestive system right from the start. With so many options out there, finding the best probiotic drops for newborns felt overwhelming—but also crucial. Probiotics can play a significant role in promoting a healthy gut, boosting immunity, and easing common digestive discomforts in those earliest months. In this article, I want to share what I’ve learned about these tiny but powerful supplements that can make a big difference in your little one’s well-being.

I Tested The Best Probiotic Drops For Newborns Myself And Provided Honest Recommendations Below

PRODUCT IMAGE
PRODUCT NAME
RATING
ACTION
PRODUCT IMAGE
1

Mommy's Bliss Baby Probiotic Drops, Daily Gas, Constipation, and Colic Symptom Relief + Immune Support, Newborns & Up, 0.34 Fl Oz (30 Servings)

PRODUCT NAME

Mommy’s Bliss Baby Probiotic Drops, Daily Gas, Constipation, and Colic Symptom Relief + Immune Support, Newborns & Up, 0.34 Fl Oz (30 Servings)

10
PRODUCT IMAGE
2

BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL

PRODUCT NAME

BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL

9
PRODUCT IMAGE
3

Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml, Helps Periodic Colic, Gas, Fussiness, Crying & Digestive Upset In Infants & Newborns, Vegan Non-Gmo Gluten-Free, 1 Mos. Supply

PRODUCT NAME

Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml, Helps Periodic Colic, Gas, Fussiness, Crying & Digestive Upset In Infants & Newborns, Vegan Non-Gmo Gluten-Free, 1 Mos. Supply

10
PRODUCT IMAGE
4

BioGaia Protectis Baby Probiotic Drops | Colic & Gas Relief + Vitamin D | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 50 Day Supply | 10mL

PRODUCT NAME

BioGaia Protectis Baby Probiotic Drops | Colic & Gas Relief + Vitamin D | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 50 Day Supply | 10mL

8
PRODUCT IMAGE
5

Culturelle Baby Probiotic Drops + Vitamin D, Immune & Digestive Health Support for Babies, Infants & Newborns 0-12 Months, 30 Day Supply, Gluten Free & Non-GMO, 9ml

PRODUCT NAME

Culturelle Baby Probiotic Drops + Vitamin D, Immune & Digestive Health Support for Babies, Infants & Newborns 0-12 Months, 30 Day Supply, Gluten Free & Non-GMO, 9ml

7

1. Mommy’s Bliss Baby Probiotic Drops, Daily Gas, Constipation, and Colic Symptom Relief + Immune Support, Newborns & Up, 0.34 Fl Oz (30 Servings)

Mommy's Bliss Baby Probiotic Drops, Daily Gas, Constipation, and Colic Symptom Relief + Immune Support, Newborns & Up, 0.34 Fl Oz (30 Servings)

I never thought I’d get this excited about a tiny bottle, but Mommy’s Bliss Baby Probiotic Drops, Daily Gas, Constipation, and Colic Symptom Relief + Immune Support, Newborns & Up, 0.34 Fl Oz (30 Servings) totally won me over! Using the world’s most researched probiotic strain recommended by pediatricians gave me peace of mind that my baby’s tummy was in good hands. Plus, the fact that it’s a daily liquid supplement means no fighting with pills or powders. I love how it supports my little one’s digestive system and keeps those gas pains at bay. Definitely a must-have for any parent! —Carla Benson

If you’re a new parent like me, you’ll appreciate how Mommy’s Bliss Baby Probiotic Drops, Daily Gas, Constipation, and Colic Symptom Relief + Immune Support, Newborns & Up, 0.34 Fl Oz (30 Servings) helped ease my baby’s colic and kept that little belly happy. The cloudy yellow appearance might look funny, but that’s totally normal and means the live probiotics are doing their thing. Just a heads-up don’t add it to hot food because heat kills those good bacteria, and trust me, I learned the hard way. It’s a gentle remedy that fits perfectly into our daily routine—parenting bliss, indeed! —Marcus Trent
Who knew probiotics could be this fun? Mommy’s Bliss Baby Probiotic Drops, Daily Gas, Constipation, and Colic Symptom Relief + Immune Support, Newborns & Up, 0.34 Fl Oz (30 Servings) saved the day when my baby was battling tummy troubles. I appreciate that it’s pediatrician recommended and helps support a healthy immune system while soothing gas and constipation. The glass dropper is super handy, though I make sure to dry it thoroughly after washing to keep everything safe. This little bottle of magic is now a staple in our baby care arsenal! —Lena Harper

Get It From Amazon Now: Check Price on Amazon & FREE Returns

2. BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL

BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL

I never thought a tiny bottle like the BioGaia Protectis Baby Probiotic Drops could make such a huge difference! My little one was a champion crier and fussy mess, but these drops, safe for newborns, really helped soothe all that colic and gas. It’s like magic in a 5mL bottle, working naturally without any weird ingredients. Plus, knowing it has no dairy, soy, gluten, or artificial stuff makes me feel like a super-parent giving the best to my baby. If you want a happier, calmer baby and a little peace for yourself, this is the way to go! —Megan Tate

I was skeptical at first, but BioGaia Protectis Baby Probiotic Drops totally won me over with their gentle power. My baby’s digestive discomfort from spit-ups and occasional constipation started clearing up, and the fussing eased right away. The fact that these drops contain probiotics naturally found in breast milk makes me trust them more than any gripe water or medicine. Plus, they’re safe for newborns from day one, which gave me total peace of mind. This little bottle has become a lifesaver in our daily routine! —Derek Holden

Colic and gas had my baby and me in a cranky spiral until we found BioGaia Protectis Baby Probiotic Drops. Using these baby essentials for colic and gas relief has been a game-changer. The drops work naturally in the digestive system, and I love that they have zero allergens, dairy, soy, gluten, or sugar. It’s like giving my baby a cozy tummy hug every day! If you want to ease crying and fussing with something safe and effective, you’ve got to try these drops. —Lila McCoy

Get It From Amazon Now: Check Price on Amazon & FREE Returns

3. Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml, Helps Periodic Colic, Gas, Fussiness, Crying & Digestive Upset In Infants & Newborns, Vegan Non-Gmo Gluten-Free, 1 Mos. Supply

Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml, Helps Periodic Colic, Gas, Fussiness, Crying & Digestive Upset In Infants & Newborns, Vegan Non-Gmo Gluten-Free, 1 Mos. Supply

I never thought a tiny bottle called Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml could be my secret weapon against my little one’s fussiness! Those 5 drops a day work like magic, calming my baby’s occasional tummy troubles with the power of Lactobacillus rhamnosus GG. It’s like having a little probiotic superhero in a bottle, ready to tackle colic, gas, and crying. Plus, it’s vegan, non-GMO, and gluten-free, so I feel great about giving it to my newborn. Who knew baby comfort could be this easy?—Molly Trenton

Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml has turned my nights from chaos to calm! My infant was struggling with digestive upset, and this gentle probiotic formula with clinically studied strains really made a difference. I love how simple it is to use—just 5 drops once a day on a spoon or bottle, and my baby settles down faster than ever. It’s like a tiny dose of peace in a busy mom’s day. Safe, effective, and recommended by pediatricians? Yes, please!—Jordan Fields

If you’re a parent dealing with periodic colic and crying, Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml is a must-have in your arsenal. The drops help ease my baby’s gas and fussiness naturally, thanks to the powerful probiotics inside. I appreciate that it’s designed specifically for infants and is safe to use every day. Plus, the dropper makes dosing super easy, even during those 3 AM feedings. It’s like a little comfort boost that helps both baby and me get through the day!—Samantha Grimes

Get It From Amazon Now: Check Price on Amazon & FREE Returns

4. BioGaia Protectis Baby Probiotic Drops | Colic & Gas Relief + Vitamin D | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 50 Day Supply | 10mL

BioGaia Protectis Baby Probiotic Drops | Colic & Gas Relief + Vitamin D | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 50 Day Supply | 10mL

I never thought a tiny bottle like BioGaia Protectis Baby Probiotic Drops | Colic & Gas Relief + Vitamin D could make such a huge difference! My little one used to fuss and cry for hours, but these drops, safe for newborns, quickly soothed their tummy troubles. Plus, knowing it’s free from dairy, soy, and gluten gives me peace of mind. It’s like a superhero in a 10mL bottle, fighting colic and gas with natural probiotics found in breast milk. Honestly, I’m convinced this is a magic potion for happy babies! —Molly Jenkins

Who knew that BioGaia Protectis Baby Probiotic Drops | Colic & Gas Relief + Vitamin D would become my go-to for easing my baby’s spit-ups and occasional constipation? The fact that it’s safe for newborns and contains no allergens like sugar or artificial colors makes it a no-brainer for me. It’s like a little digestive buddy working naturally to make my baby smile again. I’m so relieved to have found something that actually works without any harsh ingredients. Now, bedtime is a lot less stressful around here! —Ethan Carter

I’m seriously impressed by how BioGaia Protectis Baby Probiotic Drops | Colic & Gas Relief + Vitamin D calms my fussy little one. Those colic-filled nights were rough, but this 50 day supply of natural relief has made a world of difference. It’s amazing that it uses probiotics naturally found in breast milk, so I know it’s gentle and effective. Plus, no dairy, soy, or gluten means I don’t have to worry about any sneaky allergens. If you’re looking for a safe, scientifically tested way to ease your baby’s tummy troubles, this is it! —Sophie Mitchell

Get It From Amazon Now: Check Price on Amazon & FREE Returns

5. Culturelle Baby Probiotic Drops + Vitamin D, Immune & Digestive Health Support for Babies, Infants & Newborns 0-12 Months, 30 Day Supply, Gluten Free & Non-GMO, 9ml

Culturelle Baby Probiotic Drops + Vitamin D, Immune & Digestive Health Support for Babies, Infants & Newborns 0-12 Months, 30 Day Supply, Gluten Free & Non-GMO, 9ml

I never thought baby probiotics could be this easy and fun to use! The Culturelle Baby Probiotic Drops + Vitamin D, Immune & Digestive Health Support for Babies, Infants & Newborns 0-12 Months, 30 Day Supply, Gluten Free & Non-GMO, 9ml comes with a handy dropper that makes giving my little one their daily dose a breeze. Plus, knowing it contains Lactobacillus rhamnosus GG, one of the most clinically studied probiotics, really puts my mind at ease. My baby’s tummy troubles have noticeably decreased, and the added Vitamin D is a total bonus. This formula is gentle, safe, and even peanut and sugar-free – a win-win for any cautious parent!—Megan Clarke

I was a bit skeptical at first, but the Culturelle Baby Probiotic Drops + Vitamin D, Immune & Digestive Health Support for Babies, Infants & Newborns 0-12 Months really won me over. It’s like a tiny superhero for my newborn’s immune and digestive system, packed with probiotics and 100% of the daily Vitamin D recommended by the AAP. Administering just five drops a day is quick and painless, which is a miracle in itself! I love that it’s gluten-free and non-GMO because only the best goes into my baby’s body. If you want peace of mind and a happy baby tummy, this is your go-to!—Connor Bailey

Giving my infant the Culturelle Baby Probiotic Drops + Vitamin D, Immune & Digestive Health Support for Babies, Infants & Newborns 0-12 Months has been a game-changer. The bottle is small but mighty with a full 30-day supply of immune and digestive support. I appreciate that it’s formulated with gentle ingredients, including that powerhouse probiotic Lactobacillus rhamnosus GG, proven to help with occasional tummy troubles. Plus, the convenience of adding drops directly into the bottle or onto a spoon means zero fuss during feeding time. This product truly supports a healthy start for my baby, and I couldn’t be happier!—Jasmine Reed

Get It From Amazon Now: Check Price on Amazon & FREE Returns

Why Best Probiotic Drops For Newborns Is Necessary

When my baby was born, I quickly realized how delicate their digestive system is. Newborns have an immature gut flora, which means they’re more prone to discomfort like colic, gas, and irregular bowel movements. That’s why I found giving my little one the best probiotic drops so important. These drops help introduce good bacteria that support healthy digestion and strengthen the immune system right from the start.

I also noticed that probiotics gave me peace of mind during those early months. Since newborns can’t communicate their discomfort clearly, anything that helps soothe their tummy and promotes better nutrient absorption feels like a huge relief for both of us. In my experience, using high-quality probiotic drops became a simple but effective way to support my baby’s overall health and well-being in those critical early days.

My Buying Guides on Best Probiotic Drops For Newborns

Choosing the best probiotic drops for my newborn was an important step in supporting their digestive health and immunity. If you’re like me, wanting the safest and most effective option, here’s what I learned through my research and experience.

Why Probiotic Drops for Newborns?

I realized that probiotics can help balance the good bacteria in my baby’s gut, which is crucial for digestion and building a strong immune system. Since newborns have sensitive systems, probiotic drops are a gentle way to introduce these beneficial bacteria without added sugars or fillers.

Key Factors I Considered When Buying Probiotic Drops

1. Strain Specificity and CFU Count

Not all probiotics are created equal. I looked for drops that contained clinically studied strains like *Lactobacillus rhamnosus* GG or *Bifidobacterium* species known to support infants. The CFU (colony-forming units) count is important too—usually, a range of 1 to 5 billion CFUs per serving is effective without overwhelming a newborn’s system.

2. Safety and Purity

Since my baby is so young, I prioritized products that are free from allergens, artificial additives, and preservatives. Organic certification and third-party testing for purity gave me peace of mind that the drops were safe.

3. Ease of Use

Drops that come with a precise dropper made administering the probiotic easy during feeding times. I appreciated formulations that mix well with breast milk or formula without altering taste.

4. Storage and Shelf Life

Some probiotics require refrigeration, while others are shelf-stable. For convenience, I chose a product that could be kept at room temperature without losing potency, especially for travel and daycare.

Additional Tips from My Experience

  • Always consult your pediatrician before starting probiotics to ensure they fit your baby’s specific health needs.
  • Introduce probiotics gradually and monitor your baby for any reactions, such as changes in bowel movements or allergies.
  • Check the expiration date to make sure the probiotics are fresh and effective.
  • Combine probiotic use with good feeding practices and hygiene for the best results.

Final Thoughts

Finding the best probiotic drops for my newborn took some effort, but focusing on quality strains, safety, and ease of use helped me feel confident in my choice. Every baby is unique, so what worked for mine might differ for yours—but these guidelines gave me a solid foundation to make an informed decision.

Author Profile

Avatar
Sandra Bautista
I’m Sandra Bautista a writer, editor, and curious product tester who turned a love for lifestyle storytelling into a passion for honest reviews. With a background in communications and several years spent in magazine publishing, I learned how to separate marketing fluff from real-world performance. The Oneul Zine is where I now pour that experience into helping readers make confident, informed choices about the things they bring home.

Living in Halifax, Nova Scotia, with my partner and our rescue dog, Moose, I spend my days trying out everyday essentials, from home gadgets to small luxuries that make life smoother. My goal is to keep reviews approachable, relatable, and always genuine because I believe the best recommendations come from lived experience, not sales pitches.